Principal Investigator of a National Research Program on Advanced Numerical Methods for Scientific Computing of the Ministero dell'Universita` e della Ricerca Scientifica e Tecnologica (M.U.R.S.T) for 1998-2000.

In the field of the Mathematical Modeling and Scientific Computation applied to Electrocardiology is a renowned expert and for his contribution in the Electrocardiographic inverse problem was awarded a Bellman Prize.

The research activity is proved by more than 60 publications and participation to several meetings and congresses and also as invited speaker, starting from Computing Methods in Applied Science and Eng. (Paris, 1979), to High Performance Biomedical Computing (Durham, 1993).

Since 1986 he is a member of the editorial board of J. Math. Biol., reviewing: NFS, NIH proposals, numerous journals, including SIAM journals, Math. Biosci., Physica D., Calcolo, Inverse Pbs., IEEE-TBME, Med. Biol. Eng. Comp., J. Cardiovasc. Electrophys., Ann. Biomed. Eng..

Principal Investigator of a Research Unit on Qualitative and quantitative modeling of metabolic and electrophysiological processes in the framework of a Special Program 1998-1999 of the National Council of Researches on Mathematical methods and models of biological and physiological phenomena. The research objective is to provide innovative mathematical methods and computational environments for the simulation of electrograms in the normal and pathological cardiac electric activity in 3-D model of the ventricular geometry.